Detalhe da pesquisa
1.
CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine.
Drug Metab Dispos
; 51(1): 29-37, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35197312
2.
Inhibition of the aromatase enzyme by exemestane cysteine conjugates.
Mol Pharmacol
; 2022 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35953090
3.
Influence of Glutathione-S-Transferase A1*B Allele on the Metabolism of the Aromatase Inhibitor, Exemestane, in Human Liver Cytosols and in Patients Treated With Exemestane.
J Pharmacol Exp Ther
; 382(3): 327-334, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35793834
4.
Drug-Drug Interaction Between Orally Administered Hydrocodone-Acetaminophen and Inhalation of Cannabis Smoke: A Case Report.
Hosp Pharm
; 57(4): 518-525, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35898257
5.
Cannabinoid Metabolites as Inhibitors of Major Hepatic CYP450 Enzymes, with Implications for Cannabis-Drug Interactions.
Drug Metab Dispos
; 49(12): 1070-1080, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34493602
6.
Characterization of Cytosolic Glutathione S-Transferases Involved in the Metabolism of the Aromatase Inhibitor, Exemestane.
Drug Metab Dispos
; 49(12): 1047-1055, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34593616
7.
Inhibition of UDP-Glucuronosyltransferase Enzymes by Major Cannabinoids and Their Metabolites.
Drug Metab Dispos
; 49(12): 1081-1089, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34493601
8.
The Novel CYP2A6 Inhibitor, DLCI-1, Decreases Nicotine Self-Administration in Mice.
J Pharmacol Exp Ther
; 372(1): 21-29, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31628204
9.
UDP-Glycosyltransferase 3A Metabolism of Polycyclic Aromatic Hydrocarbons: Potential Importance in Aerodigestive Tract Tissues.
Drug Metab Dispos
; 48(3): 160-168, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31836608
10.
Altered Metabolism of Polycyclic Aromatic Hydrocarbons by UDP-Glycosyltransferase 3A2 Missense Variants.
Chem Res Toxicol
; 33(11): 2854-2862, 2020 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32993298
11.
Potential Regulation of UGT2B10 and UGT2B7 by miR-485-5p in Human Liver.
Mol Pharmacol
; 96(6): 674-682, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31554697
12.
Regulation of UGT2A1 by miR-196a-5p and miR-196b-5p.
J Pharmacol Exp Ther
; 369(2): 234-243, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30850392
13.
Role of l- and d-Menthol in the Glucuronidation and Detoxification of the Major Lung Carcinogen, NNAL.
Drug Metab Dispos
; 47(12): 1388-1396, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578206
14.
Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.
Drug Metab Dispos
; 47(5): 535-544, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804050
15.
Prominent Stereoselectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues.
Chem Res Toxicol
; 32(8): 1689-1698, 2019 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31307193
16.
Carbonyl reduction of NNK by recombinant human lung enzymes: identification of HSD17ß12 as the reductase important in (R)-NNAL formation in human lung.
Carcinogenesis
; 39(8): 1079-1088, 2018 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29788210
17.
Regulation of UGT2B Expression and Activity by miR-216b-5p in Liver Cancer Cell Lines.
J Pharmacol Exp Ther
; 359(1): 182-93, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474751
18.
Impact of Genetic Variants in the Nicotine Metabolism Pathway on Nicotine Metabolite Levels in Smokers.
Cancer Epidemiol Biomarkers Prev
; 32(1): 54-65, 2023 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36252563
19.
Cannabinoids and drug metabolizing enzymes: potential for drug-drug interactions and implications for drug safety and efficacy.
Expert Rev Clin Pharmacol
; 15(12): 1443-1460, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36384377
20.
Comparison of tobacco-specific nitrosamine levels in smokeless tobacco products: High levels in products from Bangladesh.
PLoS One
; 15(5): e0233111, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32453764